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Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution
Thiamine pyrophosphate (TPP)-sensitive mRNA domains are the most prevalent riboswitches known. Despite intensive investigation, the complex ligand recognition and concomitant folding processes in the TPP riboswitch that culminate in the regulation of gene expression remain elusive. Here, we used sin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600479/ https://ncbi.nlm.nih.gov/pubmed/23440214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218062110 |
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