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Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution

Thiamine pyrophosphate (TPP)-sensitive mRNA domains are the most prevalent riboswitches known. Despite intensive investigation, the complex ligand recognition and concomitant folding processes in the TPP riboswitch that culminate in the regulation of gene expression remain elusive. Here, we used sin...

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Detalles Bibliográficos
Main Authors: Haller, Andrea, Altman, Roger B., Soulière, Marie F., Blanchard, Scott C., Micura, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600479/
https://ncbi.nlm.nih.gov/pubmed/23440214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218062110
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