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Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups

A set of modified 2′-deoxyribonucleoside triphosphates (dNTPs) bearing a linear or branched alkane, indole or phenyl group linked through ethynyl or alkyl spacer were synthesized and used as substrates for polymerase synthesis of hypermodified DNA by primer extension (PEX). Using the alkyl-linked dN...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Ondruš, Marek, Sýkorová, Veronika, Bednárová, Lucie, Pohl, Radek, Hocek, Michal
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708046/
https://ncbi.nlm.nih.gov/pubmed/33152081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa999
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