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Sugar modified pyrimido[4,5-b]indole nucleosides: synthesis and antiviral activity

Three types of sugar modified pyrimido[4,5-b]indole nucleosides (2′-deoxy-2′-fluororibo-, 2′-deoxy-2′-fluoroarabino- and arabinonucleosides) were synthesized by glycosylation of 4,6-dichloropyrimido[4,5-b]indole followed by modification of sugar moiety and introduction of substituents into position...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Konč, Juraj, Tichý, Michal, Pohl, Radek, Hodek, Jan, Džubák, Petr, Hajdúch, Marián, Hocek, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084004/
https://ncbi.nlm.nih.gov/pubmed/30108897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00319f
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