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Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions

A nucleoside bearing a solvatochromic push–pull fluorene fluorophore (dC(FL)) was designed and synthesized by the Sonogashira coupling of alkyne-linked fluorene 8 with 5-iodo-2′-deoxycytidine. The fluorene building block 8 and labeled nucleoside dC(FL) exerted bright fluorescence with significant so...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Dziuba, Dmytro, Pospíšil, Petr, Matyašovský, Ján, Brynda, Jiří, Nachtigallová, Dana, Rulíšek, Lubomír, Pohl, Radek, Hof, Martin, Hocek, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021979/
https://ncbi.nlm.nih.gov/pubmed/30034716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02548j
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