Significance of host heparanase in promoting tumor growth and metastasis

Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, angiogenesis and metastasis. Much of the impact of heparanase on tumor progression is related to its function in mediating tumor-host crosstalk, priming the tumor micro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Matrix Biol
Prif Awduron: Zhang, Gan-Lin, Gutter-Kapon, Lilach, Ilan, Neta, Batool, Tahira, Singh, Kailash, Digre, Andreas, Luo, Zhengkang, Sandler, Stellan, Shaked, Yuval, Sanderson, Ralph D., Wang, Xiao-Min, Li, Jin-Ping, Vlodavsky, Israel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704762/
https://ncbi.nlm.nih.gov/pubmed/32534153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2020.06.001
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