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Heparanase is required for activation and function of macrophages

The emerging role of heparanase in tumor initiation, growth, metastasis, and chemoresistance is well recognized and is encouraging the development of heparanase inhibitors as anticancer drugs. Unlike the function of heparanase in cancer cells, very little attention has been given to heparanase contr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gutter-Kapon, Lilach, Alishekevitz, Dror, Shaked, Yuval, Li, Jin-Ping, Aronheim, Ami, Ilan, Neta, Vlodavsky, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137702/
https://ncbi.nlm.nih.gov/pubmed/27849593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611380113
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