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Heparanase and chemotherapy synergize to drive macrophage activation and enhance tumor growth

The emerging role of heparanase in tumor initiation, growth, metastasis, and chemoresistance is well recognized, encouraging the development of heparanase inhibitors as anticancer drugs. Unlike the function of heparanase in cancer cells, little attention has been given to heparanase contributed by c...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Bhattacharya, Udayan, Gutter-Kapon, Lilach, Kan, Tal, Boyango, Ilanit, Barash, Uri, Yang, Shi-Ming, Liu, JingJing, Gross-Cohen, Miriam, Sanderson, Ralph D., Shaked, Yuval, Ilan, Neta, Vlodavsky, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942624/
https://ncbi.nlm.nih.gov/pubmed/31690669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1676
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