Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer

Heparanase, the sole heparan sulfate (HS) degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis, and inflammation. Heparanase accomplishes this by degrading HS and thereby facilitating cell invasion and regulating the bioavailability...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Katz, Amit, Barash, Uri, Boyango, Ilanit, Feld, Sari, Zohar, Yaniv, Hammond, Edward, Ilan, Neta, Kremer, Ran, Vlodavsky, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922397/
https://ncbi.nlm.nih.gov/pubmed/29721203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25022
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