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Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer
Heparanase, the sole heparan sulfate (HS) degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis, and inflammation. Heparanase accomplishes this by degrading HS and thereby facilitating cell invasion and regulating the bioavailability...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922397/ https://ncbi.nlm.nih.gov/pubmed/29721203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25022 |
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