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Heparanase enhances myeloma progression via CXCL10 down regulation

In order to explore the mechanism(s) underlying the pro-tumorigenic capacity of heparanase we established an inducible Tet-on system. Heparanase expression was markedly increased following addition of doxycycline (Dox) to the culture medium of CAG human myeloma cells infected with the inducible hepa...

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Detalhes bibliográficos
Main Authors: Barash, Uri, Zohar, Yaniv, Wildbaum, Gizi, Beider, Katia, Nagler, Arnon, Karin, Nathan, Ilan, Neta, Vlodavsky, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185261/
https://ncbi.nlm.nih.gov/pubmed/24699306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.121
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