Modification of heparanase gene expression in response to conditioning and LPS treatment: strong correlation to rs4693608 SNP

Heparanase is an endo-β-glucuronidase that specifically cleaves the saccharide chains of HSPGs, important structural and functional components of the ECM. Cleavage of HS leads to loss of the structural integrity of the ECM and release of HS-bound cytokines, chemokines, and bioactive angiogenic- and...

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Bibliografiske detaljer
Main Authors: Ostrovsky, Olga, Shimoni, Avichai, Baryakh, Polina, Morgulis, Yan, Mayorov, Margarita, Beider, Katia, Shteingauz, Anna, Ilan, Neta, Vlodavsky, Israel, Nagler, Arnon
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2014
Fag:
Systems Biology & Immunogenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046248/
https://ncbi.nlm.nih.gov/pubmed/24319286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0313147
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