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Inverse correlation between HPSE gene single nucleotide polymorphisms and heparanase expression: possibility of multiple levels of heparanase regulation

Heparanase is an endo-β-glucuronidase that specifically cleaves the saccharide chains of heparan sulfate proteoglycans. Heparanase plays important roles in processes such as angiogenesis, tumor metastasis, tissue repair and remodeling, inflammation and autoimmunity. Genetic variations of the heparan...

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Detalles Bibliográficos
Main Authors: Ostrovsky, Olga, Korostishevsky, Michael, Shafat, Itay, Mayorov, Margarita, Ilan, Neta, Vlodavsky, Israel, Nagler, Arnon
Formato: Artigo
Idioma:Inglês
Publicado: The Society for Leukocyte Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796676/
https://ncbi.nlm.nih.gov/pubmed/19406828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1208735
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