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Genetic variations in the heparanase gene (HPSE) associate with increased risk of GVHD following allogeneic stem cell transplantation: effect of discrepancy between recipients and donors

Graft-versus-host disease (GVHD) is the most common cause of nonrelapse mortality and morbidity after hematopoietic stem cell transplantation (HSCT). The well-documented involvement of heparanase in the process of inflammation and autoimmunity led us to investigate an association between HPSE gene s...

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Библиографические подробности
Главные авторы: Ostrovsky, Olga, Shimoni, Avichai, Rand, Avital, Vlodavsky, Israel, Nagler, Arnon
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844015/
https://ncbi.nlm.nih.gov/pubmed/20075159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236455
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