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Function from within: Autophagy induction by HPSE/heparanase—new possibilities for intervention

HPSE (heparanase) is the predominant enzyme in mammals capable of cleaving heparan sulfate, an activity highly implicated in cellular invasion and tumor metastasis. HPSE expression is induced in many types of cancer and increased HPSE levels are most often associated with increased tumor metastasis...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Ilan, Neta, Shteingauz, Anna, Vlodavsky, Israel
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835213/
https://ncbi.nlm.nih.gov/pubmed/26571129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1115174
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