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Function from within: Autophagy induction by HPSE/heparanase—new possibilities for intervention

HPSE (heparanase) is the predominant enzyme in mammals capable of cleaving heparan sulfate, an activity highly implicated in cellular invasion and tumor metastasis. HPSE expression is induced in many types of cancer and increased HPSE levels are most often associated with increased tumor metastasis...

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Publicat a:Autophagy
Autors principals: Ilan, Neta, Shteingauz, Anna, Vlodavsky, Israel
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835213/
https://ncbi.nlm.nih.gov/pubmed/26571129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1115174
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