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Heparanase regulation of cancer, autophagy and inflammation: New mechanisms and targets for therapy

Because of its impact on multiple biological pathways, heparanase has emerged as a major regulator of cancer, inflammation and other disease processes. Heparanase accomplishes this by degrading heparan sulfate which regulates the abundance and location of heparin-binding growth factors thereby influ...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Sanderson, Ralph D., Elkin, Michael, Rapraeger, Alan C., Ilan, Neta, Vlodavsky, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226874/
https://ncbi.nlm.nih.gov/pubmed/27758044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13932
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