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Heparanase regulation of cancer, autophagy and inflammation: New mechanisms and targets for therapy
Because of its impact on multiple biological pathways, heparanase has emerged as a major regulator of cancer, inflammation and other disease processes. Heparanase accomplishes this by degrading heparan sulfate which regulates the abundance and location of heparin-binding growth factors thereby influ...
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| Veröffentlicht in: | FEBS J |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5226874/ https://ncbi.nlm.nih.gov/pubmed/27758044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13932 |
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