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Heparanase: Busy at the cell surface
Heparanase activity is strongly implicated in structural remodeling of the extracellular matrix underlying tumor and endothelial cells that leads to cellular invasion. In addition, heparanase augments signaling cascades leading to enhanced phosphorylation of selected protein kinases and increased ge...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755511/ https://ncbi.nlm.nih.gov/pubmed/19733083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2009.06.005 |
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