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Opposing functions of heparanase-1 and heparanase-2 in cancer progression
Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis and inflammation. Heparanase accomplishes this by degrading heparan sulfate and thereby regulating the bioavailability of heparin-binding prote...
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| Argitaratua izan da: | Trends Biochem Sci |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741533/ https://ncbi.nlm.nih.gov/pubmed/29162390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2017.10.007 |
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