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Opposing functions of heparanase-1 and heparanase-2 in cancer progression
Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis and inflammation. Heparanase accomplishes this by degrading heparan sulfate and thereby regulating the bioavailability of heparin-binding prote...
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| Publicado no: | Trends Biochem Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741533/ https://ncbi.nlm.nih.gov/pubmed/29162390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2017.10.007 |
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