Heparanase: from basic research to therapeutic applications in cancer and inflammation

Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, angiogenesis and metastasis. Heparanase expression is enhanced in almost all cancers examined including various carcinomas, sarcomas and hematological malignancies. Num...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Resist Updat
Main Authors: Vlodavsky, Israel, Singh, Preeti, Boyango, Ilanit, Gutter-Kapon, Lilach, Elkin, Michael, Sanderson, Ralph D., Ilan, Neta
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447241/
https://ncbi.nlm.nih.gov/pubmed/27912844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2016.10.001
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