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Heparanase: from basic research to therapeutic applications in cancer and inflammation
Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, angiogenesis and metastasis. Heparanase expression is enhanced in almost all cancers examined including various carcinomas, sarcomas and hematological malignancies. Num...
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| Publicado no: | Drug Resist Updat |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5447241/ https://ncbi.nlm.nih.gov/pubmed/27912844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2016.10.001 |
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