Impact of Heparanase and the Tumor Microenvironment on Cancer Metastasis and Angiogenesis: Basic Aspects and Clinical Applications

Heparanase is an endo-β-D-glucuronidase that cleaves heparan sulfate (HS) side chains at a limited number of sites, activity that is strongly implicated with cell invasion associated with cancer metastasis, a consequence of structural modification that loosens the extracellular matrix barrier. Hepar...

Full description

Saved in:
Bibliographic Details
Main Authors: Vlodavsky, Israel, Elkin, Michael, Ilan, Neta
Format: Artigo
Language:Inglês
Published: Rambam Health Care Campus 2011
Subjects:
Discoveries from the Bench to the Bedside
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678787/
https://ncbi.nlm.nih.gov/pubmed/23908791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5041/RMMJ.10019
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items