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Heparanase: from basic research to therapeutic applications in cancer and inflammation
Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, angiogenesis and metastasis. Heparanase expression is enhanced in almost all cancers examined including various carcinomas, sarcomas and hematological malignancies. Num...
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| Опубликовано в: : | Drug Resist Updat |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5447241/ https://ncbi.nlm.nih.gov/pubmed/27912844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2016.10.001 |
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