Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer

Heparanase, the sole heparan sulfate (HS) degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis, and inflammation. Heparanase accomplishes this by degrading HS and thereby facilitating cell invasion and regulating the bioavailability...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Katz, Amit, Barash, Uri, Boyango, Ilanit, Feld, Sari, Zohar, Yaniv, Hammond, Edward, Ilan, Neta, Kremer, Ran, Vlodavsky, Israel
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922397/
https://ncbi.nlm.nih.gov/pubmed/29721203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25022
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