Significance of host heparanase in promoting tumor growth and metastasis

Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, angiogenesis and metastasis. Much of the impact of heparanase on tumor progression is related to its function in mediating tumor-host crosstalk, priming the tumor micro...

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Udgivet i:Matrix Biol
Main Authors: Zhang, Gan-Lin, Gutter-Kapon, Lilach, Ilan, Neta, Batool, Tahira, Singh, Kailash, Digre, Andreas, Luo, Zhengkang, Sandler, Stellan, Shaked, Yuval, Sanderson, Ralph D., Wang, Xiao-Min, Li, Jin-Ping, Vlodavsky, Israel
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704762/
https://ncbi.nlm.nih.gov/pubmed/32534153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2020.06.001
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