Significance of host heparanase in promoting tumor growth and metastasis

Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, angiogenesis and metastasis. Much of the impact of heparanase on tumor progression is related to its function in mediating tumor-host crosstalk, priming the tumor micro...

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Publicado en:Matrix Biol
Autores principales: Zhang, Gan-Lin, Gutter-Kapon, Lilach, Ilan, Neta, Batool, Tahira, Singh, Kailash, Digre, Andreas, Luo, Zhengkang, Sandler, Stellan, Shaked, Yuval, Sanderson, Ralph D., Wang, Xiao-Min, Li, Jin-Ping, Vlodavsky, Israel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704762/
https://ncbi.nlm.nih.gov/pubmed/32534153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2020.06.001
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