Carregant...
Preclinical and clinical development of therapeutic antibodies targeting functions of CD47 in the tumor microenvironment
CD47 is a ubiquitously expressed cell surface glycoprotein that functions as a signaling receptor for thrombospondin-1 and as the counter-receptor for signal regulatory protein-α (SIRPα). Engaging SIRPα on macrophages inhibits phagocytosis, and CD47 thereby serves as a physiological marker of self....
Guardat en:
| Publicat a: | Antib Ther |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7687918/ https://ncbi.nlm.nih.gov/pubmed/33244513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbaa017 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|