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Therapeutic targeting of the thrombospondin-1 receptor CD47 to treat liver cancer

CD47 is a signaling receptor for the matricellular protein thrombospondin-1 and a counter-receptor for signal regulatory protein-α (SIRPα) on macrophages. Following its initial discovery in 1992 as a cell surface protein that is over-expressed by ovarian carcinoma, elevated CD47 expression has emerg...

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Detalhes bibliográficos
Publicado no:J Cell Commun Signal
Main Authors: Roberts, David D., Kaur, Sukhbir, Soto-Pantoja, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414848/
https://ncbi.nlm.nih.gov/pubmed/25779848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-015-0283-9
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