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Therapeutic Targeting of CD47 to Modulate Tissue Responses to Ischemia and Radiation

CD47 is a widely expressed cell surface receptor that serves as a counter-receptor for signal regulatory protein-α and as a receptor for the secreted matricellular protein thrombospondin-1. Thrombospondin-1 signaling through CD47 regulates cellular signaling pathways that control cell survival, grow...

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Detalhes bibliográficos
Main Authors: Soto-Pantoja, David R., Isenberg, Jeff S., Roberts, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368437/
https://ncbi.nlm.nih.gov/pubmed/22685691
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