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Thrombospondin-1 and CD47 Limit Cell and Tissue Survival of Radiation Injury
Radiation, a primary mode of cancer therapy, acutely damages cellular macromolecules and DNA and elicits stress responses that lead to cell death. The known cytoprotective activity of nitric oxide (NO) is blocked by thrombospondin-1, a potent antagonist of NO/cGMP signaling in ischemic soft tissues,...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2543077/ https://ncbi.nlm.nih.gov/pubmed/18787106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080237 |
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