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Thrombospondin-1-CD47 Blockade Following Ischemia Reperfusion Injury is Tissue Protective
BACKGROUND: Nitric oxide has pro-survival effects that can limit ischemia-reperfusion (I/R) injuries. However, the matrix glycoprotein thrombospondin-1 is induced following I/R injury and limits nitric oxide signaling by engaging its cell surface receptor CD47. We herein examine whether post-injury...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794041/ https://ncbi.nlm.nih.gov/pubmed/19952644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0b013e3181bceec3 |
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