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Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling
Radiation-induced damage of normal tissues restricts the therapeutic doses of ionizing radiation that can be delivered to tumors and thereby limits the effectiveness of radiotherapy. Thrombospondin-1 signaling through its cell surface receptor CD47 limits recovery from several types of stress, and m...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811586/ https://ncbi.nlm.nih.gov/pubmed/20161613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000139 |
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