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CD47 deficiency confers cell and tissue radioprotection by activation of autophagy

Accidental or therapeutic exposure to ionizing radiation has severe physiological consequences and can result in cell death. We previously demonstrated that deficiency or blockade of the ubiquitously expressed receptor CD47 results in remarkable cell and tissue protection against ischemic and radiat...

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Autori principali: Soto-Pantoja, David R., Miller, Thomas W., Pendrak, Michael L., DeGraff, William G., Sullivan, Camille, Ridnour, Lisa A., Abu-Asab, Mones, Wink, David A., Tsokos, Maria, Roberts, David D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494592/
https://ncbi.nlm.nih.gov/pubmed/22874555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21562
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