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CD47 deficiency confers cell and tissue radioprotection by activation of autophagy

Accidental or therapeutic exposure to ionizing radiation has severe physiological consequences and can result in cell death. We previously demonstrated that deficiency or blockade of the ubiquitously expressed receptor CD47 results in remarkable cell and tissue protection against ischemic and radiat...

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Hlavní autoři: Soto-Pantoja, David R., Miller, Thomas W., Pendrak, Michael L., DeGraff, William G., Sullivan, Camille, Ridnour, Lisa A., Abu-Asab, Mones, Wink, David A., Tsokos, Maria, Roberts, David D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494592/
https://ncbi.nlm.nih.gov/pubmed/22874555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21562
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