CD47 Receptor Globally Regulates Metabolic Pathways That Control Resistance to Ionizing Radiation

Modulating tissue responses to stress is an important therapeutic objective. Oxidative and genotoxic stresses caused by ionizing radiation are detrimental to healthy tissues but beneficial for treatment of cancer. CD47 is a signaling receptor for thrombospondin-1 and an attractive therapeutic target...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Miller, Thomas W., Soto-Pantoja, David R., Schwartz, Anthony L., Sipes, John M., DeGraff, William G., Ridnour, Lisa A., Wink, David A., Roberts, David D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Metabolism
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598996/
https://ncbi.nlm.nih.gov/pubmed/26311851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665752
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