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CD47 Receptor Globally Regulates Metabolic Pathways That Control Resistance to Ionizing Radiation

Modulating tissue responses to stress is an important therapeutic objective. Oxidative and genotoxic stresses caused by ionizing radiation are detrimental to healthy tissues but beneficial for treatment of cancer. CD47 is a signaling receptor for thrombospondin-1 and an attractive therapeutic target...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Miller, Thomas W., Soto-Pantoja, David R., Schwartz, Anthony L., Sipes, John M., DeGraff, William G., Ridnour, Lisa A., Wink, David A., Roberts, David D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598996/
https://ncbi.nlm.nih.gov/pubmed/26311851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665752
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