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CD47 Receptor Globally Regulates Metabolic Pathways That Control Resistance to Ionizing Radiation

Modulating tissue responses to stress is an important therapeutic objective. Oxidative and genotoxic stresses caused by ionizing radiation are detrimental to healthy tissues but beneficial for treatment of cancer. CD47 is a signaling receptor for thrombospondin-1 and an attractive therapeutic target...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Miller, Thomas W., Soto-Pantoja, David R., Schwartz, Anthony L., Sipes, John M., DeGraff, William G., Ridnour, Lisa A., Wink, David A., Roberts, David D.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598996/
https://ncbi.nlm.nih.gov/pubmed/26311851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665752
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