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Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47

INTRODUCTION: CD47 is a ubiquitously expressed cell surface receptor that serves as a counter-receptor for SIRPα in recognition of self by the innate immune system. Independently, CD47 also functions as an important signaling receptor for regulating cell responses to stress. AREAS COVERED: We review...

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Detalhes bibliográficos
Main Authors: Soto-Pantoja, David R., Stein, Erica V., Rogers, Natasha M., Sharifi-Sanjani, Maryam, Isenberg, Jeffrey S., Roberts, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564224/
https://ncbi.nlm.nih.gov/pubmed/23101472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.733699
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