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Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47
INTRODUCTION: CD47 is a ubiquitously expressed cell surface receptor that serves as a counter-receptor for SIRPα in recognition of self by the innate immune system. Independently, CD47 also functions as an important signaling receptor for regulating cell responses to stress. AREAS COVERED: We review...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564224/ https://ncbi.nlm.nih.gov/pubmed/23101472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.733699 |
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