Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice

Deficiencies in many coagulation factors and protease-activated receptors (PARs) affect embryonic development. We describe a defect in definitive erythropoiesis in PAR2-deficient mice. Embryonic PAR2 deficiency increases embryonic death associated with variably severe anemia in comparison with PAR2-...

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Udgivet i:Blood Adv
Main Authors: Saffarzadeh, Mona, Grunz, Kristin, Nguyen, T. Son, Lee, Young K., Kitano, Maki, Danckwardt, Sven, Rodrigues, Carina D. S., Weiler, Hartmut, Reyda, Sabine, Ruf, Wolfram
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686899/
https://ncbi.nlm.nih.gov/pubmed/33232477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003299
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