EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice

Infection and inflammation are invariably associated with activation of the blood coagulation mechanism, secondary to the inflammation-induced expression of the coagulation initiator tissue factor (TF) on innate immune cells. By investigating the role of cell-surface receptors for coagulation factor...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Liang, Hai Po H., Kerschen, Edward J., Hernandez, Irene, Basu, Sreemanti, Zogg, Mark, Botros, Fady, Jia, Shuang, Hessner, Martin J., Griffin, John H., Ruf, Wolfram, Weiler, Hartmut
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2015
Sujets:
Thrombosis and Hemostasis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424632/
https://ncbi.nlm.nih.gov/pubmed/25733582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-610717
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires