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Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice

The key effector molecule of the natural protein C pathway, activated protein C (aPC), exerts pleiotropic effects on coagulation, fibrinolysis, and inflammation. Coagulation-independent cell signaling by aPC appears to be the predominant mechanism underlying its highly reproducible therapeutic effic...

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發表在:Blood
Main Authors: Liang, Hai Po H., Kerschen, Edward J., Basu, Sreemanti, Hernandez, Irene, Zogg, Mark, Jia, Shuang, Hessner, Martin J., Toso, Raffaella, Rezaie, Alireza R., Fernández, José A., Camire, Rodney M., Ruf, Wolfram, Griffin, John H., Weiler, Hartmut
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653768/
https://ncbi.nlm.nih.gov/pubmed/26341257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644401
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