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Organ-specific protection against LPS-induced vascular leak is dependent on the endothelial protein C receptor (EPCR)
OBJECTIVE: To study the role of the endothelial protein C receptor (EPCR) in the modulation of susceptibility to inflammation-induced vascular leak in vivo. APPROACH/RESULTS: Genetically modified mice with low, <10%-EPCR expression (EPCR(low)) and control mice were challenged with lipopolysacchar...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735365/ https://ncbi.nlm.nih.gov/pubmed/23393392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301082 |
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