Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice

Deficiencies in many coagulation factors and protease-activated receptors (PARs) affect embryonic development. We describe a defect in definitive erythropoiesis in PAR2-deficient mice. Embryonic PAR2 deficiency increases embryonic death associated with variably severe anemia in comparison with PAR2-...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Saffarzadeh, Mona, Grunz, Kristin, Nguyen, T. Son, Lee, Young K., Kitano, Maki, Danckwardt, Sven, Rodrigues, Carina D. S., Weiler, Hartmut, Reyda, Sabine, Ruf, Wolfram
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686899/
https://ncbi.nlm.nih.gov/pubmed/33232477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003299
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