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ACTIVATED PROTEIN C IN SEPSIS: THE PROMISE OF NON-ANTICOAGULANT ACTIVATED PROTEIN C

PURPOSE OF REVIEW: Discuss the potential use of recombinant activated protein C (aPC) variants with altered bioactivity in sepsis therapy. RECENT FINDINGS: Since the initial PROWESS trial demonstrating efficacy of aPC to reduce mortality of severe sepsis, follow-up studies have failed to resolve con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Weiler, Hartmut, Ruf, Wolfram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742321/
https://ncbi.nlm.nih.gov/pubmed/18695372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0b013e32830abdf4
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