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ACTIVATED PROTEIN C IN SEPSIS: THE PROMISE OF NON-ANTICOAGULANT ACTIVATED PROTEIN C
PURPOSE OF REVIEW: Discuss the potential use of recombinant activated protein C (aPC) variants with altered bioactivity in sepsis therapy. RECENT FINDINGS: Since the initial PROWESS trial demonstrating efficacy of aPC to reduce mortality of severe sepsis, follow-up studies have failed to resolve con...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742321/ https://ncbi.nlm.nih.gov/pubmed/18695372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0b013e32830abdf4 |
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