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Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice

Marrow adipocytes and osteoblasts differentiate from common mesenchymal progenitors in a mutually exclusive manner, and diversion of these progenitors toward adipocytes in old age has been proposed to account for the decline in osteoblasts and the development of involutional osteoporosis. This idea...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Almeida, Maria, Kim, Ha‐Neui, Han, Li, Zhou, Daohong, Thostenson, Jeff, Porter, Ryan M., Ambrogini, Elena, Manolagas, Stavros C., Jilka, Robert L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681065/
https://ncbi.nlm.nih.gov/pubmed/33048436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13247
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