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Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice

Marrow adipocytes and osteoblasts differentiate from common mesenchymal progenitors in a mutually exclusive manner, and diversion of these progenitors toward adipocytes in old age has been proposed to account for the decline in osteoblasts and the development of involutional osteoporosis. This idea...

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Библиографические подробности
Опубликовано в: :Aging Cell
Главные авторы: Almeida, Maria, Kim, Ha‐Neui, Han, Li, Zhou, Daohong, Thostenson, Jeff, Porter, Ryan M., Ambrogini, Elena, Manolagas, Stavros C., Jilka, Robert L.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681065/
https://ncbi.nlm.nih.gov/pubmed/33048436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13247
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