Receptor Activator of Nuclear Factor κB Ligand (RANKL) Protein Expression by B Lymphocytes Contributes to Ovariectomy-induced Bone Loss

Production of the cytokine receptor activator of NFκB ligand (RANKL) by lymphocytes has been proposed as a mechanism by which sex steroid deficiency causes bone loss. However, there have been no studies that functionally link RANKL expression in lymphocytes with bone loss in this condition. Herein,...

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Autores principales: Onal, Melda, Xiong, Jinhu, Chen, Xinrong, Thostenson, Jeff D., Almeida, Maria, Manolagas, Stavros C., O'Brien, Charles A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436192/
https://ncbi.nlm.nih.gov/pubmed/22782898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377945
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