The RANKL Distal Control Region Is Required for the Increase in RANKL Expression, But Not the Bone Loss, Associated with Hyperparathyroidism or Lactation in Adult Mice

Osteoclast-mediated bone resorption plays an essential role in calcium homeostasis and lactation. The cytokine receptor activator of nuclear factor κB ligand (RANKL) is one of a number of factors that controls the production, survival, and activity of osteoclasts. Calciotropic hormones, such as PTH,...

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Main Authors: Onal, Melda, Galli, Carlo, Fu, Qiang, Xiong, Jinhu, Weinstein, Robert S., Manolagas, Stavros C., O'Brien, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2012
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275157/
https://ncbi.nlm.nih.gov/pubmed/22207718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1149
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