Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency

Parathyroid hormone (PTH) excess stimulates bone resorption. This effect is associated with increased expression of the osteoclastogenic cytokine receptor activator of nuclear factor кB ligand (RANKL) in bone. However, several different cell types, including bone marrow stromal cells, osteocytes, an...

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Detalhes bibliográficos
Main Authors: Xiong, Jinhu, Piemontese, Marilina, Thostenson, Jeff D., Weinstein, Robert S., Manolagas, Stavros C., O’Brien, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125539/
https://ncbi.nlm.nih.gov/pubmed/24933342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.06.006
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