RANKL (Receptor Activator of NFκB Ligand) Produced by Osteocytes Is Required for the Increase in B Cells and Bone Loss Caused by Estrogen Deficiency in Mice

The cytokine receptor activator of NFκB ligand (RANKL) produced by osteocytes is essential for osteoclast formation in cancellous bone under physiological conditions, and RANKL production by B lymphocytes is required for the bone loss caused by estrogen deficiency. Here, we examined whether RANKL pr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fujiwara, Yuko, Piemontese, Marilina, Liu, Yu, Thostenson, Jeff D., Xiong, Jinhu, O'Brien, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122756/
https://ncbi.nlm.nih.gov/pubmed/27733688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742452
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