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RANKL (Receptor Activator of NFκB Ligand) Produced by Osteocytes Is Required for the Increase in B Cells and Bone Loss Caused by Estrogen Deficiency in Mice

The cytokine receptor activator of NFκB ligand (RANKL) produced by osteocytes is essential for osteoclast formation in cancellous bone under physiological conditions, and RANKL production by B lymphocytes is required for the bone loss caused by estrogen deficiency. Here, we examined whether RANKL pr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Fujiwara, Yuko, Piemontese, Marilina, Liu, Yu, Thostenson, Jeff D., Xiong, Jinhu, O'Brien, Charles A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122756/
https://ncbi.nlm.nih.gov/pubmed/27733688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742452
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