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Parathyroid Hormone Controls Receptor Activator of NF-κB Ligand Gene Expression via a Distant Transcriptional Enhancer

RANKL, a protein essential for osteoclast development and survival, is stimulated by parathyroid hormone (PTH) via a PTH receptor 1/cyclic AMP (cAMP)/protein kinase A (PKA)/CREB cascade, exclusively in osteoblastic cells. We report that a bacterial artificial chromosome-based transcriptional reporte...

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Detalhes bibliográficos
Main Authors: Fu, Qiang, Manolagas, Stavros C., O'Brien, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592840/
https://ncbi.nlm.nih.gov/pubmed/16914731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00356-06
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