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Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice

Marrow adipocytes and osteoblasts differentiate from common mesenchymal progenitors in a mutually exclusive manner, and diversion of these progenitors toward adipocytes in old age has been proposed to account for the decline in osteoblasts and the development of involutional osteoporosis. This idea...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Almeida, Maria, Kim, Ha‐Neui, Han, Li, Zhou, Daohong, Thostenson, Jeff, Porter, Ryan M., Ambrogini, Elena, Manolagas, Stavros C., Jilka, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681065/
https://ncbi.nlm.nih.gov/pubmed/33048436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13247
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