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Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11
We previously reported a peptoid ligand for the proteasomal ubiquitin receptor Rpn13 called KDT-11 and demonstrated that this compound is toxic to multiple myeloma (MM) cells, but not non-malignant cells. We show here that KDT-11 decreases the viability of a variety of cancer cell lines, especially...
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| Publié dans: | Cell Chem Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680388/ https://ncbi.nlm.nih.gov/pubmed/32857986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.08.008 |
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