Targeting proteasome ubiquitin receptor Rpn13 in multiple myeloma

Proteasome inhibitor bortezomib is an effective therapy for relapsed and newly diagnosed multiple myeloma (MM); however, dose-limiting toxicities and the development of resistance can limit its long-term utility. Recent research has focused on targeting ubiquitin receptors upstream of 20S proteasome...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Leukemia
Main Authors: Song, Y, Ray, A, Li, S, Das, DS, Tai, YT, Carrasco, RD, Chauhan, D, Anderson, KC
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749253/
https://ncbi.nlm.nih.gov/pubmed/27118409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.97
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